Three people including a teenage girl have been charged with acts to endanger life after an alleged drive-by shooting at a bus stop in Adelaide's north on New Year's Day.

Police say four people were waiting at a bus shelter on Montague Road when two shots were fired from a passing car just before midday.

They say the shooting happened after an earlier confrontation at the bus stop between the two groups but do not know if they were known to each other.

A description of the car led police to a house on nearby Lock Crescent where they made three arrests and seized a .22 calibre rifle.

Detective Chief Inspector Brian Smith says the growing number of gun crimes in Adelaide is concerning.

"It's not a good way to start the New Year and if we can get rid of firearms off the streets it would be the best thing we could do," he said.

A 30-year-old woman and a 15-year-old girl from Pooraka were charged but have been released on bail.

A 34-year-old man from Modbury was also charged.

No one was injured in the shooting.