The former baseball teammates of murdered Melbourne man Chris Lane will form a guard of honour at his funeral.

The baseball players will join Mr Lane's old school mates and loved ones to farewell the 22-year-old at St Therese's Church in Essendon on Wednesday.

Tim Sullivan, who played with Mr Lane at the Essendon Baseball Club, says the idea for the guard of honour was warmly embraced by Mr Lane's family.

"It's an acknowledgement of what Chris meant to the mates that he played with and we're there with him and will never forget him and he's close to us," he told AAP.

Mr Sullivan says the mark of respect also recognises that the players will be there to offer support to those touched by the untimely death of Mr Lane, whom he describes as the "up-and-coming junior that we took under our wing".

Up to 70 people from the club alone are expected to attend the 11.30am service.

"Most of the club will be there," club president Tony Cornish said.

Mr Lane, from Melbourne's Oak Park, was jogging alone in Duncan, Oklahoma, on August 16 when he was shot in the back during a random attack.

He was attending a college in Oklahoma where he had a baseball scholarship.

Tony Paatsch, principal at St Bernard's College from where Mr Lane graduated in 2008, says a number of staff will attend his funeral.

"We've been in contact with the family as have a number of staff, current and past, to pass on their condolences," he said.

Bernie Cronin, representing the school's Old Collegians, will attend and he expects a large turnout of Mr Lane's classmates.

Mr Cronin says the school community has been numbed by the tragedy.

"He was developing his natural talents as an athlete, as a baseball player, doing something very constructive in life, so the sudden and the tragic nature of it leaves people fairly numb," he said.

The collegians have set up a donation fund for a permanent memorial, possibly a sports scholarship.

Mr Lane's girlfriend of four years, Sarah Harper, has travelled to Melbourne from the US with her family.

The funeral will be followed by a private burial.