2003 Wimbledon (3R) — lost to Paradorn Srichaphan (ranked 11), 6-4, 6-4, 6-2.

2003 U.S. Open (2R) — lost to Younes El Aynaoui (21), 7-6 (6), 6-3, 7-6 (6).

2004 Australian Open (3R) — lost to Lleyton Hewitt (11), 7-6 (2), 7-6 (5), 6-2.

2004 Davis Cup (RR) — lost to Jiri Novak (16), 7-6 (2), 6-3, 7-6 (3).

2004 U.S. Open (2R) — lost to Andy Roddick (2), 6-0, 6-3, 6-4.

2007 Australian Open (QF) — lost to Fernando Gonzalez (9), 6-2, 6-4, 6-3.

2008 Australian Open (SF) — lost to Jo-Wilfried Tsonga (38), 6-2, 6-3, 6-2.

2009 U.S. Open (SF) — lost to Juan Martin del Potro (6), 6-2, 6-2, 6-2.

2011 Australian Open (QF) — lost to David Ferrer (7), 6-4, 6-2, 6-3.

2013 Wimbledon (1R) — lost to Steve Darcis (135), 7-6 (4), 7-6 (8), 6-4.

Nadal trailed Andy Murray 6-3, 7-6 (2), 3-0 in the quarterfinal of the 2010 Australian Open before retiring.

 

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