Residents in low-lying parts of the Bundaberg region in southern Queensland are being advised to move to higher ground.
Up to 200 millimetres of rain is expected to fall in some isolated areas over the next 24 hours.
Bundaberg Mayor Mal Forman says there is no immediate flood threat for the Burnett River catchment but it is important residents take precautions.
"We are advising people to take precautions," he said.
"Anyone who may be in a low-lying area to take those precautions now and do any things they need to do to pack things up or start to look at possible moving.
"At this point in time it's still at only the minor thing and we should not get the flooding here at this stage."
Councillor Forman says authorities are also monitoring the Kolan River and Baffle Creek.
"There's still a lot of rain around - fortunately it's not really in the Bundaberg area yet as heavy as it has been," he said.
Weather bureau hydrologist Jess Carey says minor flooding can be expected in Gayndah and Mundubbera, south-west of Bundaberg.
"Major flood levels are expected at Myvah and Tiaro, minor flood levels expected at Maryborough.
"We've seen minor to major flooding in the Barker and Baramba creek system, which are the creeks that drain the country around Kingaroy and Murgon.
"They're going to be joining up with river levels that are moving downstream from the upper Burnett River.
"At this stage we're looking at possibly moderate flooding at Walla, minor at Gayndah and Mundubbera."
More than a dozen businesses in Maryborough could be flooded later this week, with a peak of up to seven metres expected in the Mary River on Thursday morning.
Fraser Coast Mayor Gerard O'Connell says businesses are making preparations.
A family of five has been rescued from a flooded property at Monto in the North Burnett.
They were picked up by S-E-S crews this afternoon.
A woman has also been rescued from her car in Monto after getting stuck in floodwaters at Airport Drive.
There has been heavy rain in the region, and a number of roads are cut.
North Burnett council CEO Mark Pitt says the situation will worsen in the next few days.
"We don't want to alarm people but they need them to be prepared," he said.
"What we have had staff doing is just notifying affected people to just be cautious as well as in the down river townships in Eidsvold and places like that.
"We are expecting this won't be more than a moderate flow in the Burnett [River] but we are just wanting people to be prepared."
Weather bureau spokesman Ken Cato says the rain will continue.
"By Friday we will probably see those showers increase to rain areas as an upper trough arc's up over us," he said.
Moderate flooding is also expected in the next few days at Dr Mays Crossing at Elliot River, the Isis River and the Burrum River at Howard.
The District Disaster Management Group says it is monitoring the situation in the North Burnett region.
Deputy coordinator Inspector Kev Gutheridge says a large volume of water is expected in the next few days.
"The start of the Burnett River is up in this particular catchment as well," he said.
"Ultimately all the water from here does make its way through the coast around Bundaberg.
"A very large volume of water has fallen last night.
"We have been in touch with the Bureau of Meteorology about it and certainly nowhere near as much concern for us as there was several weeks ago."
Meanwhile, the North Burnett Regional Council says farmers in Monto, west of Bundaberg, are bracing for moderate flooding today.
Mayor Don Waugh says while water levels at Monal Creek are starting to fall, levels at Three Moon Creek are rising.
"If the banks break again then more fences are going to go and that's certainly going to be the case at Monto at this stage," he said.
"Cattle Creek has gone across the road north of Monto and it's cut the road between Monto and Biloela so that amount of water is going to cause some damage in that area."
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