Researchers are testing a vaccine against the most common strain of meningococcal disease.
The Adelaide Women's and Children's Hospital will evaluate its safety for adults and adolescents.
Associate Professor Helen Marshall said there were up to 300 cases annually in Australia, most the B-strain.
"In the future when the vaccine is available we'll be able to eliminate meningococcal disease and that's very important because it's a bacteria that causes such severe disease, unfortunately with 10-20 per cent of children dying if they become infected with it," she said.
"It really predominates, causes disease in the under fives and the adolescent age group, so about 65 to 70 per cent of cases actually occur in children."
There is already a vaccine for use against meningococcal-C.